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Tuberous Sclerosis
2009年1月22日 星期四
TSC1 & TSC2 proteins alignment
TSC1
基因與
TSC2
基因雖名稱相似,但生成的蛋白質─HAMARTIN與TUBE-
RIN─卻有顯著的差異,因此
TSC1
基因與
TSC2
基因不可被歸類為同一基因家族 (gene family)。上圖為CLC sequence viewer 5胺基酸序列比對的結果,TSC1 (HAMARTIN) 與TSC2 (TUBERIN) 的胺基酸序列有明顯的差異。
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2009
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Introduction of tuberous sclerosis (MIM 191100)
Molecular mechanism of tuberous sclerosis
TSC1 gene (MIM 605284)
TSC2 gene (MIM 191092)
TSC1 & TSC2 proteins alignment
TSC1-Orthologous proteins alignment
TSC1-Phylogenetic analysis
TSC2-Orthologous proteins alignment
TSC2-Phylogenetic analysis
HAMARTIN-Family information
TUBERIN-Family information
p53 pathway by glucose deprivation
Insulin/IGF pathway-protein kinase B signaling cas...
HAMARTIN-Protein sequence characterization
TUBERIN-Protein sequence characterization
HAMARTIN-Topology prediction
TUBERIN-Topology prediction
HAMARTIN-Coiled coil prediction
TUBERIN-Coiled coil prediction
HAMARTIN-Leucine zipper prediction
TUBERIN-Leucine zipper prediction
HAMARTIN-Pattern and profile search
TUBERIN-Pattern and profile search
HAMARTIN-Phosphorylation site prediction
TUBERIN-Phosphorylation site prediction
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Maxwell (M9705001)
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